Issaqueena Lake features 7 miles of hiking trails near Clemson, SC.
"From Clemson, take SC 133 north toward Six Mile, SC. Go 3.6 miles and turn left onto Old Six mile highway just past the gas station on the left. Turn right at first gravel road with the large gate. Go down this dirt road about 0.5 miles and trailhead is on the left at parking area.
http://www.tripleblaze.com/trail.php?c=3&i=347